Session: 03-07-01: Innovative Product Design and Manufacturing

Paper Number: 113512

113512 - Advancement of AM Technology in Development of Personalized In-Vivo and In-Vitro Prosthetic Implants 

The design and development of orthopedic implants using Additive Manufacturing (AM)
technology have created a new pathway for the medical healthcare sector. AM has rapidly
developed over the past few decades and has revolutionized in all fields. With advancements in
AM technology, prosthetic implants can now be customized to suit the specific needs of each
patient, leading to more effective treatment outcomes. There is a growing demand for
personalized implants as these can be made in accordance with the unique anatomy of a patient.
AM technology has enabled manufacturers to develop knee and elbow implants with a perfect
fit, and in a shorter time. Personalized implants are also expected to become more affordable
with the advancement of AM technology.
In-vivo prosthetic implants are designed to replace a missing or damaged body part and
can be used for a variety of applications such as dental implants, joint replacements, and even
heart valves. AM technology allows for the production of personalized implants with complex
geometries that are difficult or impossible to achieve using traditional manufacturing methods.
Additionally, AM can produce implants from biocompatible materials that can be tailored to
meet the specific mechanical, chemical, and biological requirements of each patient.
In-vitro prosthetic implants are designed to aid in the testing and development of drugs
and medical devices. These implants can be used to simulate the in-vivo environment, allowing
researchers to test the safety and efficacy of their products before conducting clinical trials. AM
technology allows for the creation of highly accurate and precise models of biological systems,
including organs, tissues, and cells, which can be used to develop new treatments and therapies.
The use of AM technology in the development of personalized in-vivo and in-vitro prosthetic
implants has many advantages.

The use of AM technology in the development of personalized in-vivo and in-vitro
prosthetic implants has many advantages. First, AM allows for the production of highly accurate
and precise implants that are tailored to the individual needs of each patient. This leads to better
treatment outcomes and improved patient satisfaction. Second, AM allows for the production of
complex geometries that are difficult or impossible to achieve using traditional manufacturing
methods. This leads to the development of new implant designs that can improve patient
outcomes and reduce the risk of complications. Third, AM allows for the use of biocompatible
materials that can be tailored to meet the specific mechanical, chemical, and biological
requirements of each patient. This leads to the development of implants that are more compatible
with the patient's body, reducing the risk of rejection and improving patient outcomes.
Additionally, the use of personalized implants requires a high degree of expertise and specialized
training, which may not be readily available in all healthcare settings.
With the help of computed technologies helps in the transformation of scanned Dicomm
images to three-dimensional digital models. This improvises the patient anatomy and paves
future ways in enhancing rapid production in human implants. Orthopedic patient needs
personalized and customized implant solutions. Currently, pre-designed standard prosthetic
implant models were primarily used for arthroplasties, which has witnessed a surge in the failure
rate during post-surgical studies. Improper fixation and bone breakage are considered primary
reasons for failures. These issues can be largely averted by developing more closely matched
customized implants.
Recently, designs of cardiovascular stents and orthopedic scaffolds were customized and
manufactured. This in turn induces a nose dive in the failure rate and enhances human physical
health. High precision and easy printable methods on complex structures using bio-materials
have influenced the next generation of the healthcare sector. The current study aims to
summarize the current innovations, limitations of developing customized implants, and future
applications of additive manufacturing in the medical field. As the technology continues to
develop, it is likely that personalized in-vivo and in-vitro prosthetic implants will become
increasingly common in healthcare settings, leading to better patient outcomes and improved
quality of life.
 

Presenting Author: Monsuru Ramoni Navajo Technical University

Presenting Author Biography: Monsuru Ramoni is an Associate Professor at NTU

Authors:

Alex Y Central Institute of Petrochemical Engineering and Technology
Ragavanantham Shanmugam Fairmont State University
Monsuru Ramoni Navajo Technical University
Arup Dey Navajo Technical University