Session: 04-11-03: Advanced Materials Processing and Property Characterization

Paper Number: 144853

144853 - Manufacturing of Polymer/magnesium Composite Scaffolds via Stereolithography 

Tissue scaffolds are developed/employed as a transitory framework to support the affected tissues and gradually degrade over the healing process. Finding the optimum material and technique for fabricating bone scaffolds has been the main focus, as implants must sustain structural strains, promote tissue proliferation, cell growth, and vascularization, and ensure biocompatibility. In this regard, polymers and their composites have found widespread use in fabricating three-dimensional (3D) porous scaffolds due to their remarkable properties. Stereolithography (SLA) is an additive manufacturing (AM) technique used to manufacture intricate and complex bone scaffolds using polymers or their composites that can be customized according to patient-specific anatomical needs- shape, size, and mechanical properties. This study explores the potential of incorporating Magnesium (Mg) nanoparticles into photocurable resin for bone implants manufactured through Stereolithography. Magnesium, a renowned metal for its biocompatibility, biodegradability, osteoconductivity, and mechanical attributes, is a suitable choice for tissue engineering. A photocurable resin was blended with different concentrations (wt.%) of Mg alloy, followed by 3D printing and photocuring to assess their printability and the impact of optimization on the 3D-printed structures. Physicochemical characterization and biocompatibility assays were conducted to evaluate the effects of magnesium incorporation on the structural integrity, degradation rate, and biological response in implants.

Keywords: Stereolithography, Mg-Polymer composites, Bone Tissue Engineering, Porous Scaffold, Additive Manufacturing, Biodegradable

 

 

 

 

Tissue scaffolds are developed/employed as a transitory framework to support the affected tissues and gradually degrade over the healing process. Finding the optimum material and technique for fabricating bone scaffolds has been the main focus, as implants must sustain structural strains, promote tissue proliferation, cell growth, and vascularization, and ensure biocompatibility. In this regard, polymers and their composites have found widespread use in fabricating three-dimensional (3D) porous scaffolds due to their remarkable properties. Stereolithography (SLA) is an additive manufacturing (AM) technique used to manufacture intricate and complex bone scaffolds using polymers or their composites that can be customized according to patient-specific anatomical needs- shape, size, and mechanical properties. This study explores the potential of incorporating Magnesium (Mg) nanoparticles into photocurable resin for bone implants manufactured through Stereolithography. Magnesium, a renowned metal for its biocompatibility, biodegradability, osteoconductivity, and mechanical attributes, is a suitable choice for tissue engineering. A photocurable resin was blended with different concentrations (wt.%) of Mg alloy, followed by 3D printing and photocuring to assess their printability and the impact of optimization on the 3D-printed structures. Physicochemical characterization and biocompatibility assays were conducted to evaluate the effects of magnesium incorporation on the structural integrity, degradation rate, and biological response in implants.

Presenting Author: Sumama Nuthana Kalva Hamad Bin Khalifa University

Presenting Author Biography: Sumama is a Ph.D. student at Hamad bin Khalifa University and is currently pursuing research on 3DP of
implants for biomedical applications. He is actively involved in the preparation of feedstock for FDM printing
and characterizations to assess their suitability. He completed his Master in Mechanical Engineering at Qatar
University with a focus on biomaterials for wound healing applications. He is passionate of finding
breakthroughs in additive manufacturing for biomedical applications for a sustainable future.

Authors:

Ambreen Afridi Hamad Bin Khalifa University
Sumama Nuthana Kalva Hamad Bin Khalifa University
Ans Al Rashid Hamad Bin Khalifa University
Muammer Koc Hamad Bin Khalifa University